A fingertip reads the autonomic state. A lab confirms it. A clinic follows through.
SamaClip is the two-minute fingertip screen behind Anubhav Life Care’s cardiometabolic clinic in Barasat. From a single reading it derives heart-rate variability, respiratory drive, oxygen saturation, non-invasive haemoglobin and a rhythm flag — then routes anything abnormal into the NABL-accredited diagnostic lab that sits behind it.
Validated on n = 175 paired screens · rolling cohort ≈ 3,200 patients · Barasat, North 24 Parganas
A single fingertip reading resolves the autonomic state and, through it, a working slice of the cardiometabolic panel.
Heart-rate variability encodes vagal tone. Photoplethysmography at five wavelengths carries haemoglobin, oxygenation and respiratory drive. Electrical activity on the same clip pins the beats down to a rhythm. Chronic disease — anaemia, dysglycaemia, occult infection, the autonomic neuropathy of long-standing diabetes — leaves its signature across these channels before it writes itself into a blood test.
Every derived signal is checked against a gold-standard instrument in the lab that sits behind the screening station.
| Derived | Unit | Sensor | Reference |
|---|---|---|---|
| Heart-rate variability | RMSSD · SDNN · LF/HF | PPG at 5 wavelengths | Clinical ECG on the same clip |
| Non-invasive haemoglobin | g/dL | Multi-wavelength absorbance | Medonic M-32 B haematology analyser |
| Oxygen saturation (SpO₂) | % | Red / IR PPG ratio | Benchtop pulse oximeter |
| Respiratory rate | breaths / min | PPG amplitude modulation | Manual counting, resting |
| Pulse transit time | ms — BP surrogate | ECG → PPG delay | Cuff sphygmomanometer |
| Rhythm — AF flag | positive / negative | Rhythm classifier on ECG | Clinician-confirmed 12-lead |
| Diabetes risk — HbA1c proxy | % | Multi-modal composite | Mindray CL-900i CLIA |
A screen alone is a rumour. The value is in what happens next.
Every SamaClip reading falls into a triage that goes through the lab. A borderline haemoglobin is checked on the haematology analyser the same day. A rhythm flag is checked against a clinical ECG. A raised HbA1c proxy is confirmed on the wet-chemistry instrument. The patient is not told a number — they are told whether they need a real test, and where to get it.
Confirmed anaemia is treated. Confirmed diabetes is enrolled in the cardiometabolic clinic. Confirmed atrial fibrillation is referred. A tuberculosis pattern routes to sputum AFB, CBNAAT and the IGRA on site. A re-screen at a defined interval closes the loop.
That handover — from a signal to a paid, confirmatory test — is what separates a screening tool from an app.
- Screen≈ 2-minute fingertip PPG + ECGCommunity camp · antenatal visit · clinic front desk
- FlagThreshold on the derived autonomic signalsHb, SpO₂, RR, HRV, AF rhythm, HbA1c proxy
- ConfirmGold-standard instrument in the same labMedonic haematology · Mindray biochemistry · CL-900i CLIA · 12-lead ECG · sputum AFB / CBNAAT / IGRA for TB
- TreatSame-day clinical decision by a physicianIron / B12 · diabetes enrolment · anticoagulation referral · anti-tubercular therapy
- Re-screenScheduled follow-up on the same clipCloses the loop; picks up non-responders
“What the screen really changes is the front door. It brings people to confirmatory testing who would never have come on their own — and the haemoglobin estimates track our lab closely.”
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